{ "_id": "6a1f1f2eb401979e734200ca", "Package": "iCARH", "Version": "2.0.2.1", "Date": "2020-08-23", "Title": "Integrative Conditional Autoregressive Horseshoe Model", "Authors@R": "c(person(\"Takoua\", \"Jendoubi\", role = c(\"aut\", \"cre\"), email = \"t.jendoubi14@imperial.ac.uk\"), person(\"Timothy M.D.\", \"Ebbels\", role = c(\"aut\"), email = \"t.ebbels@imperial.ac.uk\") )", "Description": "Implements the integrative conditional autoregressive\nhorseshoe model discussed in Jendoubi, T., Ebbels, T.M.\nIntegrative analysis of time course metabolic data and\nbiomarker discovery. BMC Bioinformatics 21, 11 (2020)\n. The model consists in three\nlevels: Metabolic pathways level modeling interdependencies\nbetween variables via a conditional auto-regressive (CAR)\ncomponent, integrative analysis level to identify potential\nassociations between heterogeneous omic variables via a\nHorseshoe prior and experimental design level to capture\nexperimental design conditions through a mixed-effects model.\nThe package also provides functions to simulate data from the\nmodel, construct pathway matrices, post process and plot model\nparameters.", "biocViews": "", "VignetteBuilder": "knitr", "License": "GPL (>= 3)", "RoxygenNote": "7.1.1", "Encoding": "UTF-8", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-16 08:07:31 UTC", "User": "root" }, "Author": "Takoua Jendoubi [aut, cre], Timothy M.D. Ebbels [aut]", "Maintainer": "Takoua Jendoubi ", "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libxml2-dev\nzlib1g-dev", "Repository": "https://takouajendoubi.r-universe.dev", "Date/Publication": 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"_userbio": { "uuid": 15359861, "type": "user", "name": "Takoua" }, "_downloads": { "count": 193, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/iCARH" }, "_mentions": 1, "_searchresults": 6, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/iCARH.html", "manual.pdf" ], "_realowner": "takouajendoubi", "_cranurl": false, "_releases": [ { "version": "1.0.0", "date": "2019-06-04" }, { "version": "2.0.0", "date": "2019-07-11" }, { "version": "2.0.1", "date": "2019-12-06" }, { "version": "2.0.1.1", "date": "2020-01-14" }, { "version": "2.0.2.0", "date": "2020-06-16" }, { "version": "2.0.2.1", "date": "2020-08-27" } ], "_exports": [ "iCARH.checkNormality", "iCARH.checkRhats", "iCARH.getARCoeff", "iCARH.getBeta", "iCARH.getDataImputation", "iCARH.getPathwaysCoeff", "iCARH.getPathwaysMat", "iCARH.getTreatmentEffect", "iCARH.mad", "iCARH.model", "iCARH.params", 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